The Use of Copper Supplementation to Improve Growth Performance and Claw Health in Young Holstein Bulls

Authors
H. Fagari-Nobijari 1
H. Amanlou 1
M. Dehghan-Banadaky 2
1 Department of Animal Science, Faculty of Agriculture, Zanjan University, Zanjan, Islamic Republic of Iran.
2 Department of Animal Science, University College of Agriculture and Natural Resources, University of Tehran, Karaj, Islamic Republic of Iran.
Abstract
This study was performed to determine the effect of copper on growth performance, blood metabolites and claw health in young Holstein bulls in a humid area in north of Iran. One hundred and two young Holstein bulls (Initial body weight= 377.3±17.1 kg) were randomly allocated to two treatments in a completely randomized design for 56 days. The treatment groups received: (1) the basal diet of no supplemental Cu (control; n= 50); (2) basal diet plus 30 mg of Cu kg-1 of Dry Matter (DM) as CuSO4 (n= 52). Animals received fresh total mixed ration for ad libitum feeding allowing 10% refusals. The groups’ Dry Matter Intake (DMI) was assessed daily. The Body Weights (BW) were recorded and jugular blood samples collected on days 0, 28 and 56. All claws of young bulls were examined every two weeks for an identification of claw lesions. Copper supplementation improved Average Daily Gain (ADG) and gain:feed (G:F;P < 0.05). Serum cholesterol decreased with Cu supplementation (P< 0.001). Serum Zn, Cu, and urea N were not affected by supplementation of Cu; however, plasma total protein (P< 0.001), and albumin (P< 0.001) were increased by a supplementation of Cu. The prevalence of lameness was 19.6% and control group had the highest Odds ratio (OR= 2.43). As a result, it is concluded that supplemental Cu might improve growth performance in the finishing bulls and decrease the prevalence of lameness.

Keywords

1. Almeida, P. E., Mullineaux, D. R., Raphael, W., Wickens, C. and Zanella, A. J. 2007. Early Detection of Lameness in Heifers with Hairy Heel Warts Using a Pressure Plate. Anim. Welf., 16: 135–137.
2. AOAC. 1999. Official Methods of Analysis. 15th Edition, Association of Official Analytical Chemists, Washington, DC, USA.
3. AOAC. 2000. Official Methods of Analysis. 17th Edition, Association of Official Analytical Chemists, Washington, DC, USA.
4. Bielfeldt, J. C., Badertscher, R., Tflle, K. H. and Krieter, J. 2005. Risk Factors Influencing Lameness and Claw Disorders in Dairy Cows. Livest. Prod. Sci., 95: 267–271.
5. Dorton, K. L., Engle, T. E., Hamar, D. W, Siciliano, P. D. and Yemm, R. S. 2003. Effects of Copper Source and Concentration on Copper Status and Immune Function in Growing and Finishing Steers. Anim. Feed Sci. Technol., 110: 31-44.
6. Engle, T. E. 2010. Trace Mineral Metabolism in Ruminants. J. Anim. Sci. 88(Suppl 2): 510 (Abstract).
7. Engel, T. E. and Spears, J. W. 2001. Performance, Carcass Characteristics, and Lipid Metabolism in Growing and Finishing Simmental Steers Fed Varying Concentrations of Copper. J. Anim. Sci., 79: 2920–2925.
8. Engel, T. E., Spears, J. W., Wright, C. L. and Odle, J. 2000a. Effects of Dietary Copper Source and Concentration on Carcass Characteristics and Lipid and Cholesterol Metabolism in Growing and Finishing Steers. J. Anim. Sci., 78: 1053–1059.
9. Engle, T. E., Spears, J. W., Xi, L. and Edens, F. W. 2000b. Dietary Copper Effects on Lipid Metabolism and Circulating Catecholamine Concentrations in Finishing Steers. J. Anim. Sci., 78: 2737–2744.
10. Engle, T. E., Fellner, V. and Spears, J. W. 2001. Copper Status, Serum Cholesterol, and Milk Fatty Acid profile in Holstein Cows Fed Varying Concentrations of Copper. J. Dairy Sci., 84: 2308–2313.
11. Enjalbert, F., Lebreton, P. and Salat, O. 2006. Effects of Copper, Zinc and Selenium status on Performance and Health in Commercial Dairy and Beef herds: Retrospective Study. J. Anim. Physiol. Anim. Nutr. 90:459-466.
12. Essig, H. W., Davis, J. D. and Smithson, L. J. 1972. Copper Sulfate in Steer Rations. J. Anim. Sci., 35: 436–439.
13. Fiske, C. H. and Subbarow, Y. 1925. The Colorimetric Determination of Phosphorus. J. boil. Chem., 66: 375–400.
14. Gressley, T. A. 2009. Zinc, Copper, Manganese, and Selenium in Dairy Cattle Rations. Proceedings of the 7th Annual Mid-Atlantic Nutrition Conference, March 2009, North Baltimore, PP: 56-71.
15. Hansen, S. L., Schlegel, P., Legleiter, L. R., Lloyd, K. E. and Spears, J. W. 2008. Bioavailability of Copper from Copper Glycinate in Steers Fed High Dietary Sulfur and Molybdenum. J. Anim. Sci., 86: 173-179.
16. Healy, J. and Tipton, K. 2007. Ceruloplasmin and What It Might Do. J. Neural. Transm., 114:777-781.
17. Holzhauer, M., Bartels, C. J. M., Döpfer, D. and Schaik, G. V. 2008. Clinical Course of Digital Dermatitis Lesions in an Endemically Infected Herd without Preventive Herd Strategies. Vet. J., 177: 222–230.
18. Ivan, M. and grieve, C. M. 1975. Effeds of Zinc, Copper, and Manganese Supplementation of High-Concentrate Ration on Digestibility, Growth, and Tissue Content of Holstein Calves. J. Dairy Sci., 58(3): 410-415.
19. Lee, S. H., Engle, T. E. and Hossner, K. L. 2002. Effects of Dietary Copper on the Expression of Lipogenic Genes and Metabolic Hormones in Steers. J. Anim. Sci., 80: 1999–2005.
20. Liepa, G. L., Beitz, D. C. and Linder, J. R. 1978. Cholesterol Synthesis in Ruminating and Nonruminating Goats. J. Nut., 108: 535–543.
21. Losinger, W. C. 2006. Economic Impacts of Reduced Milk Production Associated with Papillomatous Digital Dermatitis in Dairy Cows in the USA. J. Dairy Res., 73: 244–256.
22. McDowell, L. R. 2003. Minerals in Animal and Human Nutrition. Second Edition, Elsevier, Amsterdam.
23. NRC. 2000. National Research Council: Nutrient Requirements of Beef Cattle. 7th Revision Edition, Natl. Acad. Press, Washington, DC.
24. Nockels, C. F., Debonis, J. and Torrent, J. 1993. Stress Induction Affects Copper and Zinc Balance in Calves Fed Organic and Inorganic Copper and Zinc Sources. J. Anim. Sci., 71: 2539-2545.
25. O’Dell, B. L. 1990. Copper. In: "Present Knowledge in Nutrition", (Ed.): Brown, M. L.. 6th Edition, ILSI Press, Washington, DC, PP. 261–267.
26. Orr, C. L., Hutcheson, D. P., Grainger, R. B., Cummins, J. M. and Mock, R. E. 1990. Serum Copper, Zinc, Calcium and Phosphorus Concentrations of Calves Stressed by Bovine Respiratory Disease and Infectious Bovine Rhinotracheitis. J. Anim. Sci., 68: 2893-2900.
27. Percival, S. S. 1998. Copper and Immunity. Am. J. Clin Nutr., 67: 1064-1068.
28. Picco, S. J., Abba, M. C., Mattioli, G. A., Fazzio, L. E., Rosa, D., De Luca, J. C. and Dulout F. N. 2004. Association between Copper Deficiency and DNA Damage in Cattle. Mutage., 19(6): 453-456.
29. Rodriguez-Lainz, A., Hird, D. W., Walker, R. L. and Read, D. H. 1996. Papillomatous-Digital Dermatitis in 458 Dairies. J. Am. Vet. Med. Associat., 209: 1464–1467.
30. Richeson J. and Kegley. E. 2011. Effect of Supplemental Trace Minerals From Injection on Health and Performance of Highly Stressed, Newly Received Beef Heifers. The professional animal scientist, 27: 461-466
31. Siperstein, M. D. 1970. Regulation of Cholesterol Biosynthesis in Normal and Malignant Tumors. Curr. Top. Cell. Regul., 2: 65–100.
32. Somers, J. G. J. C, Frankena, K., Noordhuizen-Stassen, E. N. and Metz, J. H. M. 2005. Risk Factors for Digital Dermatitis in Dairy Cows Kept in Cubicle Houses in The Netherlands. Prevent. Vet. Med., 71: 11–21.
33. Spears, J. W. and Weiss, W. P. 2008. Role of Antioxidants and Trace Elements in Health and Immunity of Transition Dairy Cows. Vet. J., 176:70-76.
34. Sprecher, D. J., Hostetler, D. E. and Kaneene, J. B. 1997. A Lamaness Scoring System that Uses Posture and Gait to Predict Dairy Cattle Reproductive Performance. Theriogenol., 47: 1179-1187.
35. Tessman, R. K., Lakritz, J., Tyler, J. W., Casteel, S. W., Williams, J. E. and Dew, R. K. 2001. Sensitivity and Specificity of Serum Copper Determination for Detection of Copper Deficiency in Feeder Calves. J. Am. Vet. Med. Assoc., 218: 756–760.
36. Torre, P. M., Harmon, R. J., Hemken, R. W., Clark, T. W., Trammell, D. S. and Smith, B. A.. 1996. Mild Dietary Copper Insufficiency Depresses Blood Neutrophil Function in Dairy Cattle. J. Nutr. Immunol. 4:3-24.
37. Van Keulen, J. and Young, B. A. 1977. Evaluation of Acid-insoluble Ash as a Natural Marker in Ruminant Digestibility Studies. J. Anim. Sci., 44: 282–287.
38. Van Soest, P. J., Robertson, J. B. and Lewis, B. A. 1991. Methods for Dietary Fiber, Neutral Detergent Fiber, and Non-Starch Polysaccharides in Relation to Animal Nutrition. J. Dairy Sci., 74: 3583–3597.
39. Wagner, J. J., Engle, T. E., Wagner, J. J., Lacey, J. L. and Walker, G. 2008. The Effects of ZinMet Brand Liquid Zinc Methionine on Feedlot Performance and Carcass Merit in Crossbred Yearling Steers. Prof. Anim. Sci., 24: 420–429
40. Ward, J. D. and Spears, J. W. 1997. Long-term Effects of Consumption of Low-copper Diets with or without Supplemental Molybdenum on Copper Status, Performance, and Carcass Characteristics of Cattle. J. Anim. Sci., 75: 3057–3065.
41. Wells, S. J., Garber, L. P. and Wagner, B. A. 1999. Papillomatous-digital Dermatitis and Associated Risk Factors in US Dairy Herds. Prevent. Vet. Med., 38: 11–24.
Journal of Agricultural Science and Technology
Volume 15, Issue 1
January and February 2013
Pages 77-86