Volume 13, Issue 2 (2011)
JAST 2011, 13(2): 203-208 |
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Goudarzi G R, Saharkhiz M J, Sattari M, Zomorodian K. Antibacterial Activity and Chemical Composition of Ajowan (Carum copticum Benth. & Hook) Essential Oil. JAST 2011; 13 (2) :203-208
URL: http://jast.modares.ac.ir/article-23-2622-en.html
URL: http://jast.modares.ac.ir/article-23-2622-en.html
1- Department of Immunology and Bacteriology¸ Medical School¸ Lorestan University of Medical Sciences, Lorestan, Islamic Republic of Iran.
2- Department of Horticultural Sciences, Collage of Agriculture, Shiraz University, Shiraz, Islamic Republic of Iran.
3- Department of Bacteriology¸ School of Medical Sciences¸ Tarbiat Modares University, Tehran, Islamic Republic of Iran
4- Department of Medical Mycology and Parasitology, School of Medicine, Shiraz University of Medical Sciences, Shiraz , Islamic Republic of Iran.
2- Department of Horticultural Sciences, Collage of Agriculture, Shiraz University, Shiraz, Islamic Republic of Iran.
3- Department of Bacteriology¸ School of Medical Sciences¸ Tarbiat Modares University, Tehran, Islamic Republic of Iran
4- Department of Medical Mycology and Parasitology, School of Medicine, Shiraz University of Medical Sciences, Shiraz , Islamic Republic of Iran.
Abstract: (7821 Views)
Gas chromatography (GC) and gas chromatography mass spectrometry (GC-MS) were employed to determine the chemical composition of essential oil obtained from dry fruits of Carum copticum. Thymol (36.7%), -terpinene (36.5%) and -cymene (21.1%) were found to be the major constituents of the oil. The anti-bacterial activities of the oil were mainly investigated against food poisoning bacteria (Salmonella thyphimorium, Pseudomonas aeruginosa, Entero-pathogenic Escherichia coli, and Staphylococcus aureus) by broth microdilution and agar diffusion methods. The oil exhibited significant anti-bacterial activities against all the examined bacteria. In conclusion, the results of this study showed that the oil of Ajowan is rich in monoterpenes and it may be used as a natural anti-bacterial agent in drug and food industries.
Keywords: Essential oil, Carum copticum, Anti-bacterial activity, Gas Chromatography Mass Spectrometry
Received: 2010/10/11 | Accepted: 2010/10/11 | Published: 2010/10/11
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